Synergy occupies a distinctive position in the depth-psychology corpus, appearing along two largely independent axes that rarely intersect. The first and most elaborated axis is theological-anthropological, concentrated in Orthodox spirituality as expounded by Coniaris and indexed in Climacus’s Ladder of Divine Ascent: here synergy (from the Greek synergoi, ‘fellow-workers with God’) designates the cooperative interplay between divine grace and human free will in the work of salvation. This tradition insists that neither pure divine monergism nor autonomous human effort alone suffices — the person must actively receive, consent, and respond, as Mary’s fiat paradigmatically demonstrates, while all efficacy remains God’s. The second axis is structural-philosophical, found in McGilchrist’s neuropsychological phenomenology: there synergy names the taut, dynamic equipoise generated when opposing forces are held in productive tension rather than neutralized into bland equilibrium — a model explicitly contrasted with mere compromise and aligned with the Heraclitean logic of opposites. A minor empirical usage appears in exercise-neuroscience literature, where combined intervention modalities are said to ‘synergize’ distinct neuroplastic effects. The theological tradition thus treats synergy as an ontological condition of spiritual becoming, while McGilchrist treats it as a structural principle of creative energy; the tension between these readings illuminates deeper questions about cooperation, opposition, and the generative power of polarity throughout the corpus.