Soul loss stands as one of the most persistent diagnostic categories in the depth-psychological tradition, serving simultaneously as ethnographic datum, clinical metaphor, and cultural diagnosis. Jung anchored the concept in comparative anthropology, equating the primitive ‘loss of soul’ with Janet’s abaissement du niveau mental — a slackening of conscious tension producing diminution of personality — and thereby transposing shamanic pathology into the vocabulary of analytical psychology. Hillman radicalized this inheritance, arguing that what archaic cultures named with precision modern psychiatry dissolves into symptom-catalogues, as illustrated by his Burghölzli vignette of the woman who had ‘lost her heart.’ For Hillman, soul loss is not metaphor but phenomenological fact: the severing of the individual’s connective tissue to myth, community, and interiority. Moore extends the diagnosis culturally, identifying rigidity, moralism, and authoritarian spirituality as symptomatic of a civilization-wide soul loss. Estés maps the condition onto feminine psychology as the theft or neglect of the ‘soulskin.’ Romanyshyn locates collective soul loss in the cultural inability to mourn. McNiff and Levine draw on shamanic frameworks to argue that contemporary trauma is structurally equivalent to soul loss and demands analogous retrieval practices. The term thus traverses individual psychopathology, feminist depth psychology, cultural criticism, and trauma theory, constituting a genuinely trans-disciplinary concept.