The autonomous psyche stands as one of the foundational constructs of the depth-psychological tradition, designating the psyche’s irreducible capacity to generate contents, figures, and dynamics independent of ego-consciousness and beyond its governance. Jung furnishes the most architecturally complete account: autonomous contents — complexes, affects, fragmentary psychic systems — intrude upon consciousness as if from a foreign power, distorting association, displacing ego responses, and operating according to their own internal logic. The cancer metaphor in the ‘Psychology and Religion’ corpus is particularly revealing: such contents constitute ‘an autonomous being capable of’ action, rendering the ego anything but master in its own house. Wilhelm’s commentary on the Golden Flower extends this to the affective register, noting that autonomous psychic contents exercise a ‘disintegrating effect on the conscious mood’ and, when sufficiently organized, assume the character of full personalities. The Tibetan Book of the Dead, read through Jung’s lens in ‘Alchemical Studies,’ treats the danger of consciousness dissolving into ‘a plurality of autonomous fragmentary systems’ as the paramount spiritual hazard. Edinger crystallizes the corollary: the psyche’s autonomous activity is the very engine of living reality, the source of fantasy as a ceaseless creative act. Samuels extends the developmental claim, arguing that each phase of growth becomes and remains an autonomous content in adult life. The stakes are not merely clinical; the denial of autonomous psychic systems, Jung insists, is a collective pathology of modernity.