The opus alchymicum occupies a privileged position in the depth-psychology corpus as the privileged analogue through which analysts — above all Jung, but also von Franz and Abraham — articulate the structure of psychological transformation. Jung’s decisive contribution was to read the alchemical work not as proto-chemistry but as an unconscious projection of the individuation process: the successive operations of dissolution, putrefaction, whitening, and reddening map the psyche’s passage through shadow, coniunctio, and self-realization. Abraham, working from a literary-historical rather than clinical vantage, treats the opus as a coherent symbolic system whose imagery permeates European literature from the medieval period onward, charting a reiterated cycle of solve et coagula that is simultaneously cosmological and spiritual. The central tension across the corpus lies between the exoteric and esoteric readings: is the opus a laboratory procedure whose symbolism accidentally mirrors psychic life, or is the psychological drama primary and the chemical language its disguise? Jung insists on the latter, finding in the alchemical corpus an alternative soteriology that contested, and complemented, the opus divinum of the Mass. Von Franz extends this reading into the patristic and Sophia traditions. Throughout, the opus alchymicum functions as the master-term that subsumes nigredo, albedo, rubedo, coniunctio, prima materia, and the philosopher’s stone into a single teleological narrative of psychic wholeness.