The Center for Transformational Psychotherapy, located at 25 Tamalpais Avenue in San Anselmo, California, was founded by Dr. Philip E. Wolfson, a psychiatrist and psychotherapist widely credited as the originator of ketamine-assisted psychotherapy as a formal clinical modality. Dr. Wolfson is the author of The Ketamine Papers, founder of both the Ketamine Training Center and the Ketamine Research Foundation, and a pioneering voice in the integration of psychedelic medicine with depth psychotherapy. The center's approach is distinctive in its refusal to separate the pharmacological from the psychological: each KAP session lasts two and a half to three hours, with full psychotherapeutic support before, during, and after the ketamine experience. The center uses sublingual lozenges and intramuscular injections rather than intravenous infusions, creating what Wolfson describes as a gentler, deeper, and more effective therapeutic experience. Beyond KAP, the center offers psychiatry, psychopharmacology, individual and couples psychotherapy, grief and bereavement counseling, substance abuse consultation, and meditation integration. Wolfson's philosophical orientation treats therapy as an adventure of the soul, emphasizing light, truth, boundaries, clarity, and introspection as the foundations of healing. The center also maintains active involvement in clinical research through its affiliation with the Ketamine Research Foundation.
Best for
Treatment-resistant depressionAnxietyPTSDGrief and bereavementSubstance use disordersExistential distressLife-threatening illness
Modalities
Depth elements
Founded by Dr. Phil Wolfson, widely regarded as the creator of the ketamine-assisted psychotherapy modality and author of The Ketamine Papers, the center embodies a deeply psychodynamic approach that treats therapy as 'an adventure of the soul, heart, and intellect.' Unlike infusion clinics, Wolfson's model integrates psychotherapy before, during, and after each ketamine session, using sublingual lozenges and intramuscular injections rather than IV drips in sterile medical settings, creating a warmer therapeutic container for depth exploration. The center's philosophical orientation emphasizes introspection, creativity, vulnerability, and the therapeutic relationship as vehicles for transformation.
Populations served
Notable staff
Philip E. Wolfson, MD — Founder, Psychiatrist, author of The Ketamine Papers, founder of Ketamine Research Foundation and Ketamine Training Center