The term ‘transmission’ occupies a notably bifurcated terrain within the depth-psychology corpus. In its neurobiological register — represented most fully by Eric Kandel’s memoirs of neuroscience — transmission denotes the electrochemical mechanism by which neurons communicate: synaptic transmission, whether chemical or electrical, is the foundational process linking action potentials across the synaptic cleft, mediating all learning, memory, and mental life at the cellular level. This physiological sense carries significant weight for depth-psychological theory insofar as it grounds affect regulation, memory consolidation, and conscious experience in verifiable biophysical events. In a wholly distinct but no less consequential register, transmission appears in contemplative and institutional contexts — Zen lineage transmission, shamanic hereditary vocation, and cultic spiritual authority — where it designates the authorised passage of insight, practice, or power from teacher to disciple across generations. Dōgen’s Record of the Transmission of the Light, Suzuki’s account of patriarchal orthodoxy, Eliade’s comparative shamanism, and Welwood’s critique of self-styled gurus each interrogate whether authentic transmission requires verifiable succession, testing, and embodied lineage. The tension between these two domains — neurochemical and initiatory — is itself revealing: both concern how something essential passes from one locus to another while preserving integrity.