Subgenual Prefrontal Cortex

The Seba library treats Subgenual Prefrontal Cortex in 3 passages, across 2 authors (including Barrett, Lisa Feldman, Khalsa, Sahib S.).

In the library

Nature Experience Reduces Rumination and Subgenual Prefrontal Cortex Activation. Proceedings of the National Academy of Sciences 112 (28): 8567–8572.

Barrett cites Bratman et al.'s finding that nature exposure directly attenuates subgenual prefrontal cortex activation alongside rumination, positioning the region as a neural substrate of self-referential negative thought amenable to environmental intervention.

Barrett, Lisa Feldman, How Emotions Are Made: The Secret Life of the Brain, 2017thesis

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Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity. Biol Psychiatry 66:407–414.

Khalsa's roadmap invokes Harrison et al.'s evidence that systemic inflammation modulates subgenual cingulate activity and mesolimbic connectivity, linking the structure to interoceptive mood dysregulation.

Khalsa, Sahib S., Interoception and Mental Health: A Roadmap, 2018supporting

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Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity. Biol Psychiatry 66:407–414.

This parallel citation reinforces that subgenual cingulate activity serves as a critical pathway through which inflammatory signals translate into affective and motivational changes.

Khalsa, Sahib S., Interoception and Mental Health: A Roadmap, 2018supporting

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