Neuroplasticity occupies a pivotal position within the depth-psychology corpus, functioning simultaneously as a biological substrate for habit formation, a mechanism of pathological entrenchment, and the very ground of therapeutic hope. The corpus does not treat the term as a novelty: Lewis traces its intellectual lineage through Hebb, Kandel, and Kornorski, establishing that synaptic modification as the basis of learning has been recognized for over a century. What distinguishes the contemporary literature is the convergence of this neuroscientific insight with clinical psychology, trauma theory, and addiction research. Lewis makes the decisive claim that addiction is learned through neuroplasticity and, crucially, that recovery depends on its restoration — framing the phenomenon not as disease but as accelerated, desire-driven learning. Siegel and Ogden extend the concept into developmental and somatic registers, arguing that relational experience shapes synaptic architecture across the lifespan and that directed mindfulness can harness neuroplastic change to dissolve trauma-organized patterns. Sugden and Li situate neuroplasticity within lifestyle-medicine and exercise-based rehabilitation paradigms, emphasizing that pathological neuroplastic changes do not reverse spontaneously. The central tension in the corpus runs between neuroplasticity as a universal, normative brain property and its co-optation by addiction, trauma, and compulsion — a tension that motivates the therapeutic project of consciously redirecting plastic change toward integration.