Within the depth-psychology corpus, ‘Life Meaning’ occupies a central and contested position, animated by three broad orientations that resist easy synthesis. The first, associated above all with Viktor Frankl’s logotherapy, asserts that meaning is a primary human motivation — not a by-product of drive or power — and that its absence constitutes a pathogenic ‘existential vacuum’ responsible for depression, aggression, and addiction. Frankl insists that meaning must be found rather than invented, that it is discovered through responsibility to a task, a person, or unavoidable suffering. The second orientation, native to Jungian and post-Jungian thought, locates life meaning in the subjective, individualising encounter with the Self. Edinger, von Franz, and Hollis argue that meaning cannot be extracted from collective or external frameworks but arises as a living, often numinous experience from within — closely allied to individuation, synchronicity, and the religious function of the psyche. The third orientation, represented by Yalom’s existential psychotherapy, acknowledges the universe’s ontological silence while pressing the clinical question: how does a meaning-seeking being construct adequate meaning in a contingent world? Across all three streams, meaninglessness is treated as a genuine psychological emergency, not merely a philosophical puzzle, and the cultivation of meaning — whether discovered, constructed, or constellated — is regarded as indispensable to psychic health and moral seriousness.