Joseph LeDoux, who was also influenced by the review, modified Cohen’s protocol for classical conditioning and applied it to the rat, developing what has emerged as the best experimental system for studying the cellular mechanisms of learned fear in mammals.
Kandel credits LeDoux with establishing the definitive rodent model for learned fear, centered on the amygdala, which subsequently anchored the molecular neuroscience of fear memory.
, In search of memory the emergence of a new science of mind, 2006thesis