The ‘hole in the soul’ — rendered in the corpus also as ‘soul-starvation’ and, in Estés’s Spanish, hambre del alma — names a condition of radical inner depletion in which the psyche’s connective tissue to instinct, meaning, and vitality has been severed or never adequately formed. The term does not denote ordinary unhappiness; it designates a structural vacancy, a missing interior substance without which experience fails to nourish. Estés frames it as the consequence of a woman’s creative life being burned to ashes by external destructiveness, leaving a ferocious, famished hunger that latches onto any substitute. Gabor Maté situates the same vacancy at the origin of addiction, linking it to Frankl’s ‘existential vacuum’ and to the early failure of self-soothing attunement. Thomas Moore approaches the phenomenon through the soul’s digestive function: when the means of transferring outer experience into interior depth are ‘plastic,’ nourishment never reaches the psyche’s stomach. Tian Dayton maps the metaphor onto a ‘God-shaped hole,’ drawing the term into the intersection of depth psychology and recovery discourse. James Hillman identifies the phenomenology in archaic ‘loss of soul’ — the condition in which tribal connection, ritual, and myth have gone dead. Marion Woodman traces soul-starvation to the body’s disavowal in perfectionist and eating-disordered patients. Across these positions a shared axis emerges: the hole is not absence but a negative presence, an appetite that compels, that is filled badly or not at all, and whose recognition is the precondition for genuine care of the soul.