Grain occupies a remarkably dense symbolic position in the depth-psychology corpus, functioning simultaneously as agricultural reality, mythological substance, alchemical prima materia, and vehicle for the most fundamental mysteries of death and renewal. Jung and Kerényi locate grain at the heart of the Eleusinian mysteries, where Demeter’s identity as earth, vegetation numen, and ‘Corn Mother’ remains productively unresolved; the showing of a single cut stalk constitutes ‘the great and marvelous mystery of perfect revelation.’ Jung further elaborates a fourfold symbolic register for grain and wine: as agricultural products, as culturally processed substances, as expressions of the seasonally dying and resurgent god, and as soul-symbols transcending any single layer of meaning. Neumann extends this into the territory of fermentation and spiritual transformation, reading the grain-into-spirit transmutation as one of humanity’s most archaic encounters with numinous change. The Gospel of John’s ‘grain of wheat’ that must die to bear fruit becomes, for Edinger and von Franz, the canonical alchemical proof-text for putrefactio and the logic of transformation through dissolution. Gregory of Nyssa deploys the grain-ear analogy to articulate resurrection. Sardello, working from an archetypal-ecological perspective, traces the progressive desouling of bread as an index of modernity’s severance from chthonic mystery. Across these positions, grain consistently marks the threshold between death and renewal, matter and spirit, the literal and the sacramental.