Within the depth-psychology corpus, ‘drugs’ occupies a contested conceptual space that spans pharmacology, cultural critique, psychospiritual inquiry, and clinical practice. The literature refuses any single valence. Flores situates drug use as an increasingly normalized cultural strategy for managing affect—a symptom of a society that has displaced human attachment with chemical regulation. Alexander broadens this into a civilizational argument: drug addiction, properly understood, is inseparable from psychosocial dislocation and the poverty of spirit engendered by modernity. Maté and Hari press the same thesis into political register, arguing that the War on Drugs perpetuates the very trauma that drives compulsive use. A distinctly different current runs through Strassman and Mahr, who rehabilitate psychedelic drugs as instruments of depth-psychological access—vehicles to unconscious material that Jungian theory is uniquely positioned to interpret. Clinical-pharmacological writing (Flores, Addenbrooke, Berridge) attends to the mechanics of tolerance, dependence, and the critical distinction between physical and psychological craving. McPheeters anchors the pharmacotherapy end of the spectrum. The animating tension across all these positions is whether drugs are fundamentally a symptom, a tool, a policy problem, or a gateway—and whether the proper response is prohibition, treatment, integration, or transformation.