the brain stem hypothesis would be falsified by clinicoanatomical methods if it could be demonstrated unequivocally that dreaming is eliminated by forebrain lesions that completely spare the brain stem.
Solms positions the clinico-anatomical method as the decisive instrument for falsifying the brainstem-REM hypothesis, arguing that forebrain lesion data can refute the dominant activation-synthesis model of dreaming.
, Dreaming and REM Sleep Are Controlled by Different Brain Mechanisms, 2000thesis