The term ‘adoption’ enters the depth-psychology corpus along several distinct vectors, none of which fully overlap. The most sustained engagement occurs within the behavioural genetics and addiction literature, where adoption studies serve as the privileged methodological instrument for disentangling genetic from environmental determinants of psychopathology. Gabor Maté offers the most rigorous critique of this methodology, arguing that the stressed circumstances compelling a biological mother to relinquish her child already constitute a prenatal environmental variable, thereby confounding the genetic inference adoption studies are designed to isolate. A second, wholly distinct register appears in classical scholarship: Erwin Rohde documents adoption in ancient Greek practice as a ritual mechanism for securing perpetual care of the ancestor’s soul, forging an indissoluble bond between inheritance, cult obligation, and family continuity. Theologically, John of Damascus and the Philokalic tradition deploy ‘adoption’ (huiothesia) as a pneumatological category—the Spirit of adoption by which the baptised cry ‘Abba, Father’—sharply distinguished from ontological Sonship. Winnicott’s bibliography preserves a clinical trace: his 1954 paper ‘Pitfalls in Adoption’ signals a psychoanalytic concern with the adoptive relational matrix. Across these registers, adoption functions simultaneously as legal fiction, soteriological gift, epidemiological confound, and developmental crucible—a term that reveals, in each disciplinary context, a foundational anxiety about origins, belonging, and the transmissibility of pathology or grace.